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M94A3055.TXT
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1994-10-25
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Document 3055
DOCN M94A3055
TI Adenosinedeaminase (ADA): indicator of evolution of the HIV infection.
DT 9412
AU Monticelll A; Balbaryski J; Lewi D; Jauregui Rueda H; COINSIDA
Fundation, Buenos Aires, Argentina.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):164 (abstract no. PB0081). Unique
Identifier : AIDSLINE ICA10/94369520
AB OBJECTIVE: 1) To determine the use of the ADA test as an indicator of
evolution of the HIV infection. 2) To evaluate the correlation between
the ADA test and the CD4+ linphocytes count values. 3) Put forward
values for the ADA test equivalent to CD4+ ones in the CDC
classification. METHODS: One hundred and ten HIV positive patients; both
sexes, average age: 28 years old, were studiet; 33 percent of the
patient studied had some kind of the infection. They were classified
according to the CDC classification, April 1992; 30 HIV negative
patients were used as controls for ADA test. The linphocytes CD4+ were
counted up by flow citometric and the ADA test by colorimetric method.
RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSIONS:
1. The ADA test can be considered as a useful marker of the evolution of
the infection by HIV. 2. It was observed correlation between ADA test
and CD4+ linphocytes count taking into account the CDC classification.
3. ADA values equivalent to the suggested ones by the CDC for the
CD4+count can be established. 4. In the 2 degree and 3 degree stages, in
presence of some kind of the TBC, It was observed that the ADA test
value was 40% above the corresponding one to the stage.
DE Adenosine Deaminase/*BLOOD Adult AIDS-Related Opportunistic
Infections/CLASSIFICATION/DIAGNOSIS/ PHYSIOPATHOLOGY Female Human
HIV Infections/CLASSIFICATION/*DIAGNOSIS/PHYSIOPATHOLOGY Leukocyte
Count Male Prognosis T4 Lymphocytes/IMMUNOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).